- Pathway Narrative:
GLP1 is a peptide hormone released upon consumption of food in order to stimulate the release of insulin.
- Peptide Hormone
- Acts as a radio signal for the cell
- Interacts with:
- Interesting Facts:
GLP-1 is produced in and secreted from enteroendocrine L-Cells in the intestine as a response to food consumption. The binding of GLP-1 to GLP1-R in beta cells results in the initiation of the insulin secretion pathway for the purpose of controlling levels of sugar in the blood.
Many major Type 2 Diabetes drugs are stuctural analogues to GLP1. Their structure is modeled after GLP1 in order to stimulate the release of insulin.