World in a Cell

Glucagon-Like Peptide 1


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Pathway Narrative:

GLP1 is a peptide hormone released upon consumption of food in order to stimulate the release of insulin.

Peptide Hormone
Acts as a radio signal for the cell
Interacts with:
Interesting Facts:

GLP-1 is produced in and secreted from enteroendocrine L-Cells in the intestine as a response to food consumption. The binding of GLP-1 to GLP1-R in beta cells results in the initiation of the insulin secretion pathway for the purpose of controlling levels of sugar in the blood.

Many major Type 2 Diabetes drugs are stuctural analogues to GLP1. Their structure is modeled after GLP1 in order to stimulate the release of insulin.

Cell Map Scale Diagram